THE SEATH LAB
Our Team.
Ciaran completed his PhD in chemistry from the University of Strathclyde in 2017 under the supervision of Dr Allan Watson studying chemoselective transition-metal catalysis. During this time he also spent time in the labs of Prof. Tom Snaddon at Indiana University working on total synthesis of complex natural products, and with Prof. Glenn Burley on the development of novel click chemistries for nucleoside bioconjugation.
He then moved to Emory University as a postdoctoral researcher working in the laboratory of Professor Nathan Jui developing novel reductive photoredox methodologies. During this time, Ciaran worked on new synthetic methods to access alkylated heterocycles and complex fluorinated scaffolds.
In 2019, Ciaran moved to Princeton University to work with Professors David MacMillan and Tom Muir where he explored new photocatalytic methods for proximity labelling to investigate critical aspects of cancer biology.
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Currently, Ciaran is an Assistant Professor of Chemistry at Scripps-UF in Jupiter, Florida.
Ciaran P. Seath, PhD
Group Leader
Meet the Team
Postdoctoral researcher
Feifei Tong
Feifei came from China and earned his PhD in organic chemistry from SIOC in 2022. His research interests during his PhD focused on transition-metal-catalysis and the synthesis of fluorinated compounds. After gaining solid training in organic chemistry and also being tired of dealing with small molecules, he joined the Seath lab in February 2023, looking for new opportunities in chemical biology. In his spare time, he loves reading and watching football matches. As an eager learner, he is ready for challenges in a different research field!
Graduate Student
Ryan Milione
Ryan graduated Northeastern University in Boston, MA and has a B.S. in Chemistry. During his four years as an undergraduate student, he also completed two six-month internships centered around immunology at Selecta Biosciences, and Moderna. After graduating, he then joined Moderna full time as a Translational Oncology Research Associate, primarily analyzing large NanoString data sets to study the immune response after intratumoral mRNA injections. Ryan then transitioned to process development at TCR2 Therapeutics, where he helped develop a lentiviral vector (LVV) manufacturing process needed to generate autologous T-cell cancer treatments. During his three years at TCR2 Therapeutics, Ryan manufactured research-grade LVVs for pre-clinical studies and optimized large scale LVV production in 1L and 2L bioreactor systems.
Born and raised in Newton, Massachusetts, Ryan is a passionate fan of New England sports teams. He even attended his first Red Sox game when he was six months old! He grew up playing soccer, basketball, and baseball and was a co-captain of his high school varsity soccer team. Since moving to Florida, he has begun refining his skills in golf, tennis, bowling, and chess—some of his favorite hobbies.
Graduate student
Cameron Douglas
Cam is a proud Hoosier from Crawfordsville, IN. He attended Eckerd College in St. Petersburg, FL, where he studied Molecular Biology and Spanish. After completing his undergraduate studies, he spent 2 years in Boston, MA, working in the labs of Vanessa Wheeler and Ricardo Mouro Pinto at Massachusetts General Hospital. There he used CRISPR screening to study genetic modifiers of somatic instability in repeat disorders such as Huntington’s Disease and Friedreich Ataxia.
Cam is a first-year graduate student, rotating in the Seath Lab. Outside of lab, he is an avid sailor and enjoys getting outdoors and on the water however possible: kiteboarding, fishing, hiking, etc. He is excited to bring his research skills and intellectual curiosity to the Seath Lab and learn how to leverage proximity labeling to explore the complex mechanisms behind disease states and pharmacological perturbations.
Product Manager
Alexa Young
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Graduate Student
Wuyue Zhou
Wuyue was born in a small town in the Northeastern part of China and grew up in Beijing. She ventured to the U.S. for her undergraduate studies, earning a B.A. in Neuroscience and Mathematics from Bates College in Lewiston, ME in 2021. During her time there, she worked on synthesizing cytosine-based TET enzyme inhibitors and assessing their potential roles in memory enhancement in mouse models. Following her graduation, Wuyue relocated to Jupiter, FL and joined Scripps, driven by her fascination with unraveling the molecular interaction mechanisms between small biomolecules and understanding their contributions to cognitive processes and disease development. She worked with Dr. Puthanveettil and investigated the roles of uncharacterized lncRNA and their impact on synapse maintenance in postsynaptic neurons in Aplysia californica. In January 2024, Wuyue joined the Seath Lab, eager to explore new opportunities in chemical biology. Her focus is on delving into proximity labeling, designing potential new labeling tools, and discovering the potential the technique holds for unraveling the previously unsolvable, complex disease mechanisms.
Outside the lab, Wuyue finds joy in reading, watching anime, and playing video games. Her love for cooking serves as a great coping mechanism during those inevitable moments when experiments don't go as planned!
Graduate Student
Hong Kai Ng
Born and raised in Singapore, Hong Kai completed his undergraduate studies in the National University of Singapore (NUS), earning a B.Sc in Pharmaceutical Science. His work at NUS focused largely on investigating the properties affecting the formation of peptide-cyclodextrin complexes and probing the promiscuity of rSAM enzymes in the Department of Pharmacy. As part of the A*STAR Research internship award, Hong Kai interned in Nanobio Lab, working with Prof. Jackie Ying and Dr. Chen Feng to synthesize ligands & linkers for oligonucleotide delivery. He continued studying oligonucleotides under Dr Dave Wee in the Institute of Molecular and Cell Biology, elucidating the effects of different chemical modifications on antisense oligonucleotides. Looking to broaden his scientific perspectives outside of Singapore, Hong Kai joined Scripps in 2023, where he is excited to push the frontiers of chemical biology in the Seath Lab.
He can often be found in the kitchen outside of lab, exploring new recipes and meal prepping. He spends the rest of his free time with his pet hedgehog momo, playing chess and badminton.
Visiting Graduate Student
Alice Long
Alice Long was born and raised in the heart of Miami, Florida. She earned a Bachelor’s degree in chemistry from Emory University in 2020. During her time at Emory, she served as an undergraduate research assistant under Dr. McDonald on synthesizing mono- and di-substituted alkenyl diols to develop a more efficient way of synthesizing a polycyclic ether core in natural products. Upon graduation, Alice was a co-op intern at GlaxoSmithKline focusing her efforts on performing small molecule synthesis on-DNA with a diverse set of building blocks for machine learning applications. She then moved to Princeton, NJ to pursue her graduate studies under the tutelage of Professor Sir David W. C. MacMillan, working on novel methods for the synthesis of polycyclic aromatics. Alice joined the group in the summer of 2024 as a visiting student to learn new techniques in chemical biology.
Graduate Student
Ryan Mitchell
Ryan was born and raised in a town outside of Houston, Texas. He completed his undergraduate studies at Texas A&M University, where he earned a bachelor’s degree in biology and a minor in neuroscience. His work at Texas A&M under Dr. Richard Gomer primarily focused on elucidating the underlying molecular pathways in cell motility, with the goal of developing a therapeutic for Acute Respiratory Distress Syndrome. In his first year at Scripps, he joined the Rumbaugh and Seath labs to pursue the development of a therapeutic for SYNGAP1-related autism disorder. Outside of the lab, Ryan enjoys watching various sports, including F1, American football, and the UFC. In addition, Ryan enjoys hobbies such as chess, cooking, and working out.
PostDog
Rebel
Rebel grew up in Atlanta, GA and developed her skills at Emory and Princeton Universities. She brings significant experience in the areas of walking, napping, and barking at other small dogs. Rebel likes salmon dinners and peanut butter.